Obstetrics & gynaecology · UKMLA & AKT

HELLP syndrome

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Severe manifestation of pre-eclampsia - Haemolysis, Elevated Liver enzymes, Low Platelets
  • Complicates ~0.5-0.9% of all pregnancies; ~10-20% of severe pre-eclampsia cases
  • Up to 30% of cases present postpartum (typically within 48 hours of delivery)

Hypertension and proteinuria may be absent or mild in up to 15-20% of HELLP cases at presentation - do not exclude HELLP based on their absence.

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