Endocrine & metabolic · UKMLA & AKT
Hypoglycaemia
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise hypoglycaemia — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Counter-regulatory cascade (in order as glucose falls): insulin suppression → glucagon (glycogenolysis/gluconeogenesis) → adrenaline (glycogenolysis, lipolysis) → cortisol + growth hormone
- Brain cannot use free fatty acids as primary fuel - explains disproportionate neurological effects
- Autonomic symptoms are caused by adrenaline release - the body's alarm signal
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