Gastroenterology · UKMLA & AKT

Ulcerative colitis

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Bloody diarrhoea - blood mixed with stool, present in virtually all cases; hallmark of UC
  • Rectal bleeding with mucus - prominent even in proctitis-only disease
  • Tenesmus and faecal urgency - driven by rectal inflammation
  • Nocturnal defecation - distinguishes from IBS (where nocturnal symptoms are rare)
  • Systemic features in active disease: fever, weight loss, fatigue

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