Clinical haematology · UKMLA & AKT

Chronic lymphocytic leukaemia (CLL)

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise chronic lymphocytic leukaemia (cll) — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Most common adult leukaemia in the UK (~25-30% of all leukaemias)
  • Clonal CD5+ B-cell disorder - failure of apoptosis → accumulation of non-functional lymphocytes
  • Median age at diagnosis ~70 years; male:female ~2:1

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